Disease and associated HLA

• Multiple sclerosis- HLA DR2


• Narcolepsy- HLA DR2


• Goodpasture’s syndrome- HLA DR2


• Sjogrens- HLA DR3


• Dermatitis herpetiformis- HLA DR3


• Celiac disease- HLA DR3


• Rheumatoid arthritis- HLA DR4


• Behcets disease – HLA B5


• Congenital adrenal hyperplasia - HLA B47


• SLE- HLA DR2,DR3


• Type 1 Diabetes – HLA DR2,DR3,DR4


• Hyperthyroidism – HLA B8,DR3


• Myasthenia gravis- HLA B8,DR3


• Tuberculoid leprosy- HLA B8,DR3


• VKH syndrome- HLA DW 15,DR4

• HLAB27 :

1. Ankylosing spondylitis,


2. Psoriaticarthritis,


3. Reiter's syndrome,


4. Reactive arthritis(Yersinia,salmonella,gonococci),


5. JRA (pauci articular)

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