Strains of organisms used for Vaccine Production

• Measles - Edmonston Zogreb Strain


• Typh-Oral - Ty21a Strain


• Chicken Pox - OKA Strain


• Rabies - Pitts Moore Strain


• BCG - Danish 1331


• Polio - Lancing, Leon, Brunhilde Strain


• Mumps- Jeryll Lynn Strain


• Yellow Fever- 17 D vaccine Strain


• Hep A - HM175/GBM strain


• Rubella- RA 27/3 Strain


• Diphtheria- Park Williams 8 Strain

Pathognomic signs of different diseases

1. Cytomegalovirus infection - Owl's eye appearance of inclusion bodies.

2. Lyme Disease - Erythema chronicum migrans.

3. Inclusion body myositis - Filamentous material seen in inclusion bodies under electron microscopy.

4. Hypocalcemia (tetany) - Trousseau sign and Chovstek sign.

5. Tetanus - Risus sardonicus.

6. Chipmunk facies - (parotid gland swelling) (Chipmunk facies is also seen in marrow expansion, secondary to Beta Thalassemia Major).

7. Leprosy - Leonine facies (thickened lion-like facial skin).

8. Measles - Koplik's spots.

9. Diphtheria - Pseudomembrane on tonsils, pharynx and nasal cavity.

10. Severe hemorrhagic pancreatitis - Grey-Turner's sign (discoloration in flank area) n Cullen's sign ( discoloration in paraumbilical region)

11. Cholera - Rice watery stool

12. Enteric fever - Rose spots in abdomen

14. Meningitis - Kernig's sign and Brudzinski's sign.

15. Cholecystitis - Murphy's sign (pain on deep inspiration when inflamed gallbladder is palpated).

16. Angina pectoris - Levine's sign (hand clutching of chest).

17. Patent ductus arteriosus - Machine like murmur.

18. Pleural Effusion - Stony dull percussion.

19. Parkinson's disease - Pill rolling tremors.

20. Whipple's disease - Oculo-Masticatory Myorhythmia.

21. Acute Myeloid Leukemia - Auer rod.

22. Multiple Sclerosis - Bilateral internuclear ophthalmoplegia.

23. Congestive heart failure - Third heart sound.

24. Pericarditis - Pericardial friction rub.

25. Neurofibromatosis I - Plexiform neurofibroma.

26. Hodgkin's lymphoma - Pain within minutes after drinking alcohol n RS cells (giant mono and multi nucleated cells).

27. Pyelonephritis - White blood cell casts.

28. Rheumatic fever - Aschoff nodules.

29. Rabies - Hydrophobia and Negri bodies.