Saturday, 30 June 2012

Carcinoma Ovary



  • Stage I – limited to one or both ovaries


    • IA – involves one ovary; capsule intact; no tumor on ovarian surface; no malignant cells in ascites or peritoneal washings

    • IB – involves both ovaries; capsule intact; no tumor on ovarian surface; negative washings

    • IC – tumor limited to ovaries with any of the following: capsule ruptured, tumor on ovarian surface, positive washings




  • Stage II – pelvic extension or implants


    • IIA – extension or implants onto uterus or fallopian tube; negative washings

    • IIB – extension or implants onto other pelvic structures; negative washings

    • IIC – pelvic extension or implants with positive peritoneal washings




  • Stage III – microscopic peritoneal implants outside of the pelvis; or limited to the pelvis with extension to the small bowel or omentum


    • IIIA – microscopic peritoneal metastases beyond pelvis

    • IIIB – macroscopic peritoneal metastases beyond pelvis less than 2 cm in size

    • IIIC – peritoneal metastases beyond pelvis > 2 cm or lymph node metastases



  • Stage IV – distant metastases to the liver or outside the peritoneal cavity


Para-aortic lymph node metastases are considered regional lymph nodes (Stage IIIC).


Key Points:4 stages, First 3 stages have subdivisions A,B,C.IVth stage has no sudivisions.


Treatment


TAH+BSO+OMENTECTOMY


Postoperative chemotherapy


Neoadjuvant chemo


Radiotherapy


Immunotherapy.


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