Showing posts with label Cancer staging. Show all posts
Showing posts with label Cancer staging. Show all posts

Saturday, 30 June 2012

Carcinoma Ovary



  • Stage I – limited to one or both ovaries


    • IA – involves one ovary; capsule intact; no tumor on ovarian surface; no malignant cells in ascites or peritoneal washings

    • IB – involves both ovaries; capsule intact; no tumor on ovarian surface; negative washings

    • IC – tumor limited to ovaries with any of the following: capsule ruptured, tumor on ovarian surface, positive washings




  • Stage II – pelvic extension or implants


    • IIA – extension or implants onto uterus or fallopian tube; negative washings

    • IIB – extension or implants onto other pelvic structures; negative washings

    • IIC – pelvic extension or implants with positive peritoneal washings




  • Stage III – microscopic peritoneal implants outside of the pelvis; or limited to the pelvis with extension to the small bowel or omentum


    • IIIA – microscopic peritoneal metastases beyond pelvis

    • IIIB – macroscopic peritoneal metastases beyond pelvis less than 2 cm in size

    • IIIC – peritoneal metastases beyond pelvis > 2 cm or lymph node metastases



  • Stage IV – distant metastases to the liver or outside the peritoneal cavity


Para-aortic lymph node metastases are considered regional lymph nodes (Stage IIIC).


Key Points:4 stages, First 3 stages have subdivisions A,B,C.IVth stage has no sudivisions.


Treatment


TAH+BSO+OMENTECTOMY


Postoperative chemotherapy


Neoadjuvant chemo


Radiotherapy


Immunotherapy.


Carcinoma Endometrium

Stage I-Tumour limited to uterine corpus


  • Stage IA: tumor limited to the endometrium

  • Stage IB: invasion of less than half the myometrium

  • Stage IC: invasion of more than half the myometrium


Stage II-Tumour confined to uterus and cervix


  • Stage IIA: endocervical glandular involvement only

  • Stage IIB: cervical stromal invasion


Stage III-Local spread confined to the pelvis


  • Stage IIIA: tumor invades serosa or adnexa, or malignant peritoneal cytology

  • Stage IIIB: vaginal metastasis

  • Stage IIIC: metastasis to pelvic or para-aortic lymph nodes


Stage IV-Distant spread/organ invasion


  • Stage IVA: invasion of the bladder or bowel

  • Stage IVB: distant metastasis, including intraabdominal or inguinal lymph nodes


Key Points:


  • 4 stages Stage I and III has 3 subdivisions A,B,C.

  • LN spread mentioned only in STAGE III AND IV


Treatment :


Stage I and II-TAH+BSO,stage II may also need adjuvant radiotherapy


Stage III and IV-TAH+BSO+postoperative radiotherapy