Showing posts with label cervix. Show all posts
Showing posts with label cervix. Show all posts

Saturday, 30 June 2012

Carcinoma Endometrium

Stage I-Tumour limited to uterine corpus


  • Stage IA: tumor limited to the endometrium

  • Stage IB: invasion of less than half the myometrium

  • Stage IC: invasion of more than half the myometrium


Stage II-Tumour confined to uterus and cervix


  • Stage IIA: endocervical glandular involvement only

  • Stage IIB: cervical stromal invasion


Stage III-Local spread confined to the pelvis


  • Stage IIIA: tumor invades serosa or adnexa, or malignant peritoneal cytology

  • Stage IIIB: vaginal metastasis

  • Stage IIIC: metastasis to pelvic or para-aortic lymph nodes


Stage IV-Distant spread/organ invasion


  • Stage IVA: invasion of the bladder or bowel

  • Stage IVB: distant metastasis, including intraabdominal or inguinal lymph nodes


Key Points:


  • 4 stages Stage I and III has 3 subdivisions A,B,C.

  • LN spread mentioned only in STAGE III AND IV


Treatment :


Stage I and II-TAH+BSO,stage II may also need adjuvant radiotherapy


Stage III and IV-TAH+BSO+postoperative radiotherapy

Carcinoma Cervix

The TNM staging system for cervical cancer is analogous to the FIGO stage.


  • Stage 0 – full-thickness involvement of the epithelium without invasion into the stroma (carcinoma in situ)


  • Stage I – limited to the cervix



    • IA – diagnosed only by microscopy; no visible lesions


      • IA1 – stromal invasion less than 3 mm in depth and 7 mm or less in horizontal spread

      • IA2 – stromal invasion between 3 and 5 mm with horizontal spread of 7 mm or less




    • IB – visible lesion or a microscopic lesion with more than 5 mm of depth or horizontal spread of more than 7 mm


      • IB1 – visible lesion 4 cm or less in greatest dimension

      • IB2 – visible lesion more than 4 cm






  • Stage II – invades beyond cervix


    • IIA – without parametrial invasion, but involve upper 2/3 of vagina

    • IIB – with parametrial invasion




  • Stage III – extends to pelvic wall or lower third of the vagina


    • IIIA – involves lower third of vagina

    • IIIB – extends to pelvic wall and/or causes hydronephrosis or non-functioning kidney




Stage IV-Distant spread


  • IVA – invades mucosa of bladder or rectum and/or extends beyond true pelvis

  • IVB – distant metastasis


Key Points:4stages, each having two subdivisions A and B.No mention of LN status,Ascites.


Treatment


Tumour <5mm-Conization(to preserve fertility)or hysterectomy


Invasive lesions not extending to abdominal viscera or distal vagina-Hysterectomy+Chemotherapy+Radiotherapy


Recurrent disease- Radiotherapy.